hairy cell leukemia | Symptoms of leukemia-how not to miss a serious illness?

Symptoms of leukemia-how not to miss a serious illness?






 



Signs of leukemia
  The symptoms of leukemia do not always have some particular characteristics. The disease can start angina as usual or manifest as fatigue, discomfort. It is very important time to pay attention to these symptoms, because the sooner will be set on the right diagnosis and proper treatment, better is the chance for recovery.


The first signs of leukemia

Leukemia (leukemia) or cancer blood cancer-do not despair blood cancer-do not despair
   Characterized in that the white blood cells reach the stop state of maturity and therefore do not fulfill their protective function. The bone marrow is where all the blood cells are formed, filled with immature white-blasted blood cells that violate the maturation of the cells and platelets of the red blood cells. Therefore, all types of leukemia are accompanied by frequent infections, septic complications, anemia and coagulation disorders.

Leukemia can develop at any age. For example, when young adults are more likely to develop acute myeloid leukemia, in which myéloblastes blood appear-granular precursors of white blood cells (granulocytes). The disease progresses rapidly and if not treat it in time, patients die from infectious complications or bleeding.

After 40 years more frequent chronic leukemia. For example, under the age of 50 years-chronic myeloid leukemia, and in a more advanced age-of chronic lymphoblastic leukemia, and hairy.

Acute leukemias often start under the pretext of certain infections, such as tonsillitis purulent tonsillitis purulent-requires bed rest strict purulent tonsillitis-requires bed rest strict
  , acute pyelonephritis, and so on. Start with a high fever, discomfort, nausea, vomiting, pain in the bones and joints. After treatment the patient continues to disturb the rise periodically temperature, weakness, discomfort, dizziness.

Among the first signs of acute leukemia may include permanent bruising on the skin, bleeding gums How to prevent bleeding gums: Important rules How to prevent bleeding gums: rules Important
  , nasal and uterine bleeding uterine bleeding outside menstruation-a sign of a severe uterine bleeding violation outside of menstruation-a sign of a serious violation
  .

But not always, even acute leukemia starts suddenly. Very often the patient feels just a malaise, weakness, loss of appetite, frequent colds. However, if you do identify and treat acute leukemia in time, it progresses rapidly, and the changes are irreversible.

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The symptoms of leukemia in adults

Chronic myeloid leukemia usually develops gradually and imperceptibly. Patients can be from several months or even years to ignore the disease and lead a normal life. They often suffer from infections, are less and less viable, there is excessive bleeding. Expressed Progression may not be for several years.

In the context of these imperceptible currents can cause exacerbations, which are called in blast crisis. The blast crisis can manifest fever, weakness, lethargy, pain in the joints, bones and frequent infections and bleeding. In these patients, the spleen is always increased, as its main goal-the destruction of excess blood cells, including explosions.

Chronic lymphoblastic leukemia in elderly people also takes place very quickly. Often the only symptom is weakness and fatigue, which is easily amortized old age. The blood of these patients revealed a large number of lymphocytes at different stages of maturation. The lymph nodes are that the onset of the disease increases in infections and then return to normal. Then gradually increase the first cervical and axillary, then other groups of lymph nodes. Typically, anemia and an increase in bleeding in the early stages of disease patients feel very comfortable. The main symptom and is usually the cause of the death of these patients are infections.

Elderly people can also develop leukemia at hairy, which is often a genetic trait. In this disease can see it on blood leukocytes with typical rough, as if torn edges having a "hairy" aspect. The disease begins slowly, imperceptibly, it manifests as weakness, sweats, sometimes fever, a general malaise. Exhausted patients often suffer from infections.

One of the most characteristic signs of hairy leukemia is a significant enlargement of the spleen, posing a threat to its injury and even rupture. The diagnosis of the illness at the appropriate time is still not placed.

The symptoms of leukemia in adults is usually expressed gently, the severity of the disease develops relatively slowly, making it difficult to diagnose. And how to identify these diseases should be as early as possible is a very important attention to the health of the patient and his family.

Galina Romanenko

Keywords:

Leukemia

Treatment of leukemia-a long, but do not despair

November 17, 2014

  Treatment of leukemia

  Treatment of leukemia should be performed for a long time and start on time, which is in the early stages of the disease. Today, there are proven techniques to completely cure the leukemia patient. Treatment in this case is given after a thorough diagnosis.

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The main methods of treatment for leukemia

Treatment of leukemia in the world today is conducted in a standardized way. It begins with the suppression of the reproduction explosions-the immature white blood cells. This method is implemented chemotherapy and radiation therapy. Unfortunately, both methods are not only inhibiting the proliferation of blastic cells, but also normal cells, so that the development of new methods, more effective, destructive and aiming explosions.

At the heart of all leukemias are chromosomal mutations (chromosome-it is part of the nucleus of the cell, which contains the genes-carriers of heredity) and the formation of blasts-immature white blood cells that flood the blood and bone marrow . The resulting explosions can be repeatedly subjected to mutation and form a clone. These are these and try to identify the clones by chromosomal analysis for then aiming to influence them using antibodies (monoclonal treatment-a type of targeted therapy, or aiming).

For the effect of chemotherapy it has been more effective in the main clinics it is affected in accordance with the patient's genotype, as well as in combination with a monoclonal treatment. Radiotherapy is often combined with monoclonal-antibody-administered with this one radioactive particles that are guaranteed to destroy the added explosions. Antibodies for the treatment of leukemia can be simple (unconjugated) are not related to other substances, and conjugates with substances to it for chemotherapy or radioactive particles are connected.

As targeted therapy used as inhibitors (blockers) of the enzymes involved in the process of dividing the explosions.

Finally, there is a time-tested method of a bone marrow transplant from a donor. Blood donors must match the patient's genotype. It is more suitable in this case, the blood relatives.

Of all these techniques, the doctor selects the most suitable for a given patient, takes the medications, their dosage and the duration of the treatment. This is how we treat leukemia in Israel, Germany, Russia and other countries in specialized clinics.

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Treatment of acute leukemia

Held in a multidisciplinary hematology service of a hospital or a specialized clinic. The treatment can be divided into the following periods:

The induction of the remission of leukemia-an intensive therapy course to suppress the reproduction of sounds using chemotherapy and radiotherapy and the realization of a state of remission (explosions must be in the bone marrow is no more 5% in the blood must not be at all);

Consolidation (consolidation) of the remission of leukemia-lasts 4-6 months;

Maintenance treatment-lasts 2-3 years.

During the treatment, special attention for the dangerous periods in the treatment of leukemia. One of them is a dangerous period of induction during which, under the influence of chemotherapy completely suppressed immunity immunity-types and characteristics of children in adults immunity-types and characteristics of children in adults

   and greatly increases the risk of infection.

Another danger is the period of time after a bone marrow transplant-the patient's body can reject the donor's cells, which is accompanied by the disastrous condition of the patient.

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Medicines for leukemia

For the treatment of leukemia using different groups of medications. For example, the most commonly used medications for chemotherapy chemotherapy-it always falls hair?   Chemotherapy-Does it always fall off the hair?

   -It is:

Methotrexate-a antineoplastic, cytostatic antimetabolites of groups of podavlyaetfermenty agents involved in cell protein metabolism, inhibits DNA synthesis and cell division;

Doxorubicin-antitumor Antibiotic antibiotic-if they will help you in the foreseeable future?  Antibiotics-if they will help you in the foreseeable future?

   Anthracyclines, which inhibits the process of cell division (mainly explosions as they fall very quickly);

Vincristine-the antitumor agent of plant origin, is an alkaloid of the periwinkle, inhibits cell division;

L-asparaginase-enzyme to the antineoplastic action to catalyze cleavage of the amino acid asparagine necessary for cell viability.

Preparations for leukemia for targeted therapy:

Gleevec (imatinib)-an anticancer drug with selective inhibitory action on an enzyme involved in the multiplication of tumor cells; Selectively inhibits cell proliferation and causes the self-destruction (apoptosis) of clones of explosions;

Rituximab-antineoplastic-monoclonal antibodies having a synthetic specificity to a detectable antigen on the surface of normal and immature B lymphocytes; Rituximab refers to the structure of immunoglobulin G; Binding to B lymphocytes, antibodies destroy precisely.

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Popular Remedies treatment of leukemia

Traditional means can be used to treat leukemia, but only under medical supervision since some medicinal plants are not combined with a medicated treatment.

For the treatment of leukemia in popular medicine used different teas: strawberry leaves, cranberries, blueberry pros and cons of blueberries: the health of the forest advantages and disadvantages of blueberries: the health of the forest

  , birch buds, chicory herbs.

Is it possible to cure leukemia? Of course you can, but more successfully treated the disease in its infancy.