Hemic malignant: definition and different varieties according to the WHO classification 2001
The definition of the main neoplasia varieties of hematopoietic cells, as proposed by the WHO classification 2001, is given: myeloid neoplasia including chronic myeloproliferative syndromes, myelodysplastic syndromes, intermediate syndromes between these two states and acute leukemias, lymphoid neoplasia including Hodgkin's lymphomas and non-Hodgkin lymphomas either B, NK/T, neoplasia histiocytic and cell Dendritic and finally mastocytosis. The different entities of each variety are reported as well as their frequency for lymphomas. It is recommended in this classification to carry the diagnosis after a multidisciplinary study confronting clinical, biology, cytological study, histopathological, Immunophénotypique and if possible cytogenetics and molecular biology. The use of this common language will make comparative studies easier in the future.
Abstract
Malignant diseases of the hematopoietic tissues according to the WHO 2001 classification
The definition of the different types of neoplasias arising from haematopoietic cells as given by the WHO classification in 2001, are summarized: myeloid neoplasiass including chronic myeloproliferative syndromes, myelodysplasic syndromes, an intermediate Group called Chronic myeloproliferative/myelodysplasic syndromes, acute myeloid leukaemia, lymphoid Neoplasias comprising Hodgkin's and Hodgkin's lymphomas, either B or NK/T, histiocytic and dendritic cell neoplasias and finally mastocytosis. The different entities of each type are mentioned as well as, for the lymphomas, their frequency. This Classification recommends a multidisciplinary approach for the diagnosis of each entity, comparing clinical and biological data, the results of cytological, histopathological and Immunophenoypic studies as well as cytogenetics and molecular biology. In the future, comparative studies will be easier, due to the international use of this common language.
Key words: Chronic myeloproliferative syndromes, myelodysplasticic syndromes, acute myeloid leukemias, Hodgkin's lymphoma, non-Hodgkin's lymphoma B or NK/T, neoplasia histiocytic and dendritic cells, mastocytosis
Keywords: Chronic myeloproliferative syndrome, Myelodysplasic syndrome, acute myeloid leukaemia, Hodgkin's lymphoma, Hodgkin's lymphoma B or NK/T, histiocytic and dendritic cell Neoplasias, mastocytosis
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